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目的 首次探讨了帕金森病(PD)的X－刀治疗,为PD找出了一条新的治疗途径.方法 8 例难治性PD病人,采用X－刀1 次140 GY 损毁VIM 治疗2 例;140 GY 分2 次治疗4 例;165 GY 3 次治疗2 例;每次间隔24 H.结果 X－刀治疗后3~24 个月随访,8 例病人消除或改善了震颤症状;轻度缓了僵直和运动减少症状;无并发症发生.神经心理学检查无显著改善.结论 X－刀可安全、无创治疗难治性PD;震颤症状改善显著;神经心理学指标短期无恢复.“,”To evaluate the effects of X knife treatment of Parkiusonism and their outcome.Methods 8 parkinson disease(PD) patients were treated by X knife. 2 patients were managed by single full dose of 140 Gy, 4 patients were treated by fractionated irradiation 140 Gy for 2 times, 2 patients were treated by fractionated irradiation by 165 Gy for 3 times.Results 3~18 months later, the tremor of 8 patients disappeared or relieved significantly, the rigidity and bradykinesia were relieved slightly. No complication has been observed. Restoring of neuropsychological improvements were not observed.Conclusions PD treated by X knife is safe, patients tremor can be relieved significantly, but neuropsychological index was not changed in this short period of time.