Severe cytomegalovirus infections in immunocompetent patients at admission as dengue mimic：Successfu

• 作 者: Suhasini Tirumala Bijayini Behera Shilpa Lingala B.Vijay Kumar Pradeep Kumar Mishra Gurunath JM HariCharan Kartik Naresh
• 机 构: Yashoda Hospital, Secunderabad, India
• 出 处: 亚太热带医药杂志（英文版）
• 发表日期: 2012年11期
• 关键词: Cytomegalovirus Immunosuppression Dengue Mimicking Ganciclovir

Cytomegalovirus (CMV) infection is associated with adverse clinical outcomes in immunosuppressed persons. The incidence and association of CMV reactivation with adverse clinical outcomes in critically ill persons lacking evidence of immunosuppression at ICU admission has received great attention in the practice of critical care medicine. Critically ill patients in ICU who had associated risk factors such as mechanical ventilation, severe sepsis, or blood transfusion are more prone to CMV activation, which in t led to increased mortality and morbidity in terms of increased ICU stay, longer duration of mechanical ventilation, and higher rates of nosocomial infections. However, severe CMV as initial presentation mimicking dengue infection is rare. We recently came across seven cases with positive CMV serology at ICU admission, which we discuss in the light of current literature.