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目的探讨尿蛋白定性阴性的老年糖尿病患者尿微量白蛋白(MA)与血清胱抑素(CysC)对诊断糖尿病早期肾损伤的临床价值。方法选择尿蛋白定性阴性的老年糖尿病患者84例,健康体检人群60例,检测尿微量白蛋白与血清胱抑素C水平。结果糖尿病患者尿微量白蛋白检出阳性率57%(48例),血清胱抑素(CysC)检出阳性率14%(12例),两者联合检测检出阳性率14%(12例)。结论尿微量白蛋白是诊断老年糖尿病早期肾损伤的敏感指标,值得推广应用。
Objective To investigate the clinical value of urine microalbumin (MA) and serum cystatin (CysC) in the diagnosis of diabetic nephropathy in patients with negative urine protein. Methods Eighty - four elderly diabetic patients with negative urine protein and 60 healthy people were enrolled in this study. Urine microalbuminuria and serum cystatin C levels were measured. Results The positive rate of urine microalbumin was found in 57% (48 cases) and serum cystatin C (14 cases) in 12 cases (12 cases). The positive rate of urine microalbumin was 14% (12 cases) . Conclusions Urine microalbumin is a sensitive index for diagnosis of early renal damage in elderly patients with diabetes mellitus, which is worth popularizing and applying.