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目的探讨轮状病毒(RV)肠炎患儿体液免疫和血锌水平变化及其相关性。方法对68例RV肠炎患儿及126例同龄健康儿童的血清免疫球蛋白及锌水平进行比较,并分析血清锌及免疫球蛋白水平的变化在疾病组中的相关性。结果 RV肠炎患儿血清锌及IgA、IgG明显低于对照组,同时疾病组中血锌与IgA、IgG水平之间存在相关性。结论 RV肠炎患儿免疫功能的降低与血清锌水平的下降存在一定的相关性。
Objective To investigate the changes of humoral immunity and blood zinc levels in children with rotavirus (RV) enteritis and their correlation. Methods Serum immunoglobulin and zinc levels in 68 children with RV enteritis and 126 healthy children of the same age were compared. The correlation between serum zinc and immunoglobulin levels in the disease group was analyzed. Results Serum zinc and IgA, IgG in children with RV enteritis were significantly lower than those in the control group. There was a correlation between serum zinc, IgA and IgG levels in the disease group. Conclusion The decrease of immune function in children with RV enteritis is related to the decrease of serum zinc level.