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目的探讨妊娠期肝内胆汁淤积症(ICP)对胎儿生长发育影响的临床意义。方法对54例ICP孕妇(Ⅰ组)和60例正常孕妇(Ⅱ组)产前进行彩色超声(彩超)检查,分别记录胎儿双顶径(BDP)、股骨长度(FL),产后记录新生儿出生时体重、新生儿身长并进行对比分析。结果ICP组与对照组胎儿双顶径、股骨长、新生儿出生时体重、新生儿身长的差异均无统计学意义,早产率差异有统计学意义。结论妊娠期肝内胆汁淤积症(ICP)对胎儿的生长发育无明显影响,但是可以引起胎儿早产。
Objective To investigate the clinical significance of intrahepatic cholestasis of pregnancy (ICP) on fetal growth and development. Methods Fifty-four pregnant women with ICP (Ⅰ group) and 60 normal pregnant women (Ⅱ group) were examined with color sonography (superscript Doppler). Prenatal bipopilitis (BDP), length of femur (FL) Weight, newborn length and comparative analysis. Results There was no significant difference in biparietal diameter, femur length, birth weight at birth, and length of newborn between ICP group and control group. The difference of preterm birth rate was statistically significant. Conclusion Intrahepatic cholestasis of pregnancy (ICP) has no significant effect on the growth and development of the fetus, but it can cause the fetus to be premature.