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目的通过观察糖尿病肾病患者的临床风险因素，总结并分析其血压控制临界值。方法选取本院2012年11月~2014年11月收治的109例糖尿病肾病患者作为观察组，同期选取86例糖尿病患者作为对照组，比较两组患者血糖、血压、血脂及基本资料，总结其临床风险因素。同时，依据糖尿病肾病24h尿蛋白标准采用ROC曲线评估患者的血压控制临界值。结果两组患者中家族史、原发病病程、收缩压、胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇及肌酐情况比较均有显著差异，具有统计学意义(<0.05)。经血压控制临界值ROC曲线分析可见糖尿病肾病患者的舒张压控制临界值为79mmHg，收缩压控制临界值为140mmHg。结论收缩压、胆固醇、高密度脂蛋白胆固醇及低密度脂蛋白胆固醇等因素均与糖尿病肾病具有密切关联，控制舒张压水平在79mmHg以下、收缩压水平在140mmHg可显著提高糖尿病肾病患者的临床安全。“,”Objective To observe the clinical risk factors in patients with diabetic nephropathy,summarize and analyze their blood pressure control threshold.Methods Hospital from November 2012 to November 2014 were treated 109 cases of diabetic nephropathy as the observation group,86 cases of diabetes earlier selected as a control group,two groups were compared glucose,blood pressure,blood lipids and basic information,summarize clinical risk factors.Meanwhile,according to diabetic nephropathy 24h urine protein standards using ROC curves to assess the patient's blood pressure control threshold.Results The two groups of patients with a family history of primary disease duration,systolic blood pressure,total cholesterol,high density lipoprotein cholesterol,low-density lipoprotein cholesterol,and creatinine were significantly dif erent compared to the situation,with statistical significance( <0.05).Blood pressure control by ROC curve analysis shows that the critical value of diabetic nephropathy in patients with diastolic blood pressure control critical value 79mmHg,systolic blood pressure control critical value 140mmHg.Conclusion Systolic blood pressure,cholesterol,high density lipoprotein cholesterol and low-density lipoprotein cholesterol and other factors associated with diabetic nephropathy is closely control ed in 79mmHg diastolic blood pressure below 140mmHg systolic blood pressure levels can significantly improve the clinical safety of patients with diabetic nephropathy.