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有关药物所致畸形的例子相当少,大部分先天畸形的原因尚未明确。本文作者提供的资料是1980年元月1日到1982年6月30日之间,试图在早孕用药与先天畸形之间找出某种关系。作者取材于西亚图Puget Sound健康合作小组,材料由计算机统计处理。调查了足月活婴6509例。所调查的先天畸形有:隐睾、先天性心脏病、染色体异常、肾畸形、唇裂和/或腭裂、四肢畸形、多发畸形、先天性白内障、耳畸形、巨结肠、神经管缺陷、肛门闭锁、腹裂、回肠狭窄、食道闭锁、内脏逆位、胆道闭锁、尿道下裂(1度以上)、指甲膑骨综合征、额缝早闭、虹膜发育不全。以上疾患诊断有疑问的均请临床遗传学家审阅后定论。血
There are relatively few examples of deformities caused by drugs, and the reason for most of the congenital malformations has not been clarified yet. The information provided by the author is from January 1, 1980 to June 30, 1982, trying to find a relationship between early pregnancy medication and congenital malformations. The author is based on the Puget Sound Health Collaboration Team in West Asia and is based on computerized statistics. 6509 cases of full-term live babies were investigated. The congenital anomalies investigated include cryptorchidism, congenital heart disease, chromosomal abnormalities, kidney deformities, cleft lip and / or cleft palate, limb deformities, multiple deformities, congenital cataract, ear deformity, megacolon, neural tube defects, anal atresia, Gastrocnemius, ileum stenosis, esophageal atresia, visceral regurgitation, biliary atresia, hypospadias (over 1 degree), nail syndrome, premature suture, iris hypoplasia. The diagnosis of these disorders are invited to review the conclusions of clinical genetics conclusion. blood