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目的 :比较和探讨糖尿病病人PLT、MPV、PDW与正常健康人的变化和差异。方法 :用日本SysmexSE 95 0 0型和SysmexNE -15 0 0型血细胞分析仪调查了 2 3 2例糖尿病病人、10 7例冠心病病人、60例糖尿病合并冠心病病人及 2 17例正常健康人的PLT、MPV、PDW。结果 :糖尿病组、冠心病组以及糖尿病冠心病合并组与对照组PLT、MPV、PDW三项指标均存在高度显著性差异 (P <0 .0 1) ,而各观察组两两之间PLT、MPV、PDW无显著性差异 (P >0 .0 5 )。各观察组PLT明显低于对照组 ,而MPV、PDW则高于对照组。结论 :应把PLT、MPV、PDW三个指标综合起来 ,成为一个统一的概念应用于临床 ,当观察到糖尿病病人有PLT降低 ,MPV、PDW增高趋势时应引起足够的重视。本结果对临床研究糖尿病并发症有一定参考价值。
Objective: To compare and explore the changes and differences of PLT, MPV, PDW and normal healthy people in diabetic patients. METHODS: Twenty-two diabetic patients, 107 patients with coronary heart disease, 60 patients with diabetes mellitus with coronary heart disease and 2 17 normal healthy subjects were investigated by Japan Sysmex SE 95 0 0 and SysmexNE-1500 blood cell analyzer PLT, MPV, PDW. Results: There were highly significant differences in PLT, MPV and PDW between diabetes mellitus group, coronary heart disease group and diabetic coronary heart disease group and control group (P <0.01) MPV, PDW no significant difference (P> 0.05). PLT in each observation group was significantly lower than that in control group, while MPV and PDW were higher than those in control group. Conclusions: The three indicators of PLT, MPV and PDW should be combined into a unified concept and should be paid more attention when the trend of PLT decrease, MPV and PDW in diabetic patients should be observed. The results of clinical studies of diabetic complications have some reference value.