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1,2-二氯乙烷(1,2-Dichloroethane,1,2-DCE)是一种卤代烃类化合物,至今已有一百多年的使用历史,分子式为CH2Cl-CH2Cl,属高毒物质,常温下为无色透明油状液体,难溶于水,易挥发,具有芳香气味,主要用于工业溶剂和粘合剂的生产,也常被用作金属脱油剂、谷物熏蒸剂等[1]。1,2-DCE因应用广泛,职业接触人数众多,中毒事故时有发生。有关调查数据显示,2006—2010年职业性急性1,2-DCE中毒事故居广东省急性职业性中毒事故第2位,占15.79%[2]。1,2-DCE中毒临床表现以中毒性脑病为主,突出表现为
1,2-Dichloroethane (1,2-DCE) is a halogenated hydrocarbon compound, which has been used for over one hundred years and has the molecular formula of CH 2 Cl-CH 2 Cl. Material, colorless, transparent, oily liquid at room temperature, insoluble in water, volatile, aromatic odor, mainly used in the production of industrial solvents and adhesives, is also often used as a metal de-oiling agent, grain fumigant [ 1]. 1,2-DCE is widely used because of its wide range of occupational exposure and frequent occurrence of poisoning accidents. According to the survey data, the occupational acute 1,2-DCE poisoning accident ranked the second place of acute occupational poisoning accident in Guangdong Province from 2006 to 2010, accounting for 15.79% [2]. 1,2-DCE poisoning clinical manifestations of toxic encephalopathy, highlighted as