Helicobacter pyloripromote gastric cancer cells invasion through a NF-κB and COX-2-mediated pathway

• 作 者: Chun-YingWu Chau-JongWang Chi-
• 机 构: GraduateInstituteofClinicalMedicine,InstituteofBiochemistry,DivisionofGastroenterology,DivisionofGas
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年21期
• 关键词: 幽门螺杆菌 细菌感染 胃癌 白介素-κB COX-2 H pylori Gastric cancer Invasion MMP-9 VEGF COX-2
• 基金项目: the Taichung Veterans General Hospital Research Grant

AIM: To examine the effects of Helicobacter pylori ( Hpylort)infection on the invasiveness of gastric cancer cells, and to elucidate its mechanism.METHODS: Gastric carcinoma cells, MKN-45, were incubatedwith CagA-positive H pylori, and cell invasion was d