论文部分内容阅读
目的观察替米沙坦与卡维地洛联合治疗老年慢性心力衰竭的疗效。方法采用随机对照方法,选取86例60岁以上的慢性心力衰竭患者,随机分为两组。观察组43例,在慢性心力衰竭常规治疗基础上,给予替米沙坦联合卡维地洛治疗;对照组43例,在慢性心力衰竭常规治疗基础上,给予卡维地洛治疗。治疗6个月后对两组患者左心室心输出量(CO)、舒张期内径(LVEDD)、左心室射血分数(LVEF)等进行对比观察。结果观察组患者总有效率95.35%,对照组患者总有效率72.09%,两组差异有统计学意义(P<0.05);在第6个月末观察组与对照组患者超声心动图指标较治疗前明显改善,且观察组改善情况优于对照组,两者比较差异有统计学意义(P<0.05)。结论替米沙坦与卡维地洛联合治疗老年慢性心力衰竭能明显改善心功能,安全可靠,值得临床借鉴。
Objective To observe the effect of telmisartan and carvedilol in the treatment of senile chronic heart failure. Methods A total of 86 patients with chronic heart failure over the age of 60 were selected and randomly divided into two groups. Observation group of 43 cases, on the basis of routine treatment of chronic heart failure, given telmisartan combined with carvedilol treatment; control group of 43 cases, in the conventional treatment of chronic heart failure, given carvedilol treatment. Left ventricular output (CO), diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF) were compared between the two groups after 6 months of treatment. Results The total effective rate was 95.35% in the observation group and 72.09% in the control group, with significant difference between the two groups (P <0.05). At the end of the 6th month, the echocardiographic parameters in the observation group and the control group were significantly higher than those before the treatment Significantly improved, and the observation group improved better than the control group, the difference was statistically significant (P <0.05). Conclusion The combination therapy of telmisartan and carvedilol can significantly improve cardiac function in elderly patients with chronic heart failure, which is safe and reliable and is worthy of clinical reference.