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目的探讨血浆纤维蛋白原(FBG)动态变化在预测急性冠脉综合征(ACS)发生中的作用。方法对我院近两年来心血管门诊确诊的100例冠心病患者每月测定1次血浆FBG,根据血浆FBG测定结果分为三组,A组:当月测定值与上月无明显变化,共47例;B组:当月测定值较上月增高明显,但不超过上月测定值的1.5倍,共33例;C组:当月测定值较上月增高非常明显,达到上月测定值的1.5倍以上,共20例。回顾性分析发生ACS患者。结果A、B、C组各有2、4、13例发生ACS,ACS发生率分别为4.26%、12.12%、65%。结论血浆FBG动态升高水平与ACS发生有明显的关系,血浆FBG动态升高水平1个月内达到1.5倍以上是近期发生ACS的重要危险信号。
Objective To investigate the role of dynamic changes of fibrinogen (FBG) in the prediction of acute coronary syndrome (ACS). Methods 100 cases of CHD patients diagnosed in cardiovascular clinics in the past two years in our hospital were tested once a month for plasma FBG. According to the results of plasma FBG determination, the patients were divided into three groups. Group A: The measured value of the month did not change significantly from the previous month In group B, the monthly measurement increased significantly over the previous month, but not more than 1.5 times of the last month’s total, with 33 cases in total. In group C, the monthly measurement was significantly higher than the previous month, reaching 1.5 times the previous month’s measurement Above, a total of 20 cases. A retrospective analysis of patients with ACS occurred. Results ACS occurred in 2, 4 and 13 cases in groups A, B and C respectively. The incidence of ACS was 4.26%, 12.12% and 65% respectively. Conclusions The dynamic increase of plasma FBG has a clear relationship with the occurrence of ACS. The dynamic increase of plasma FBG within 1.5 months in 1 month is an important risk signal of recent ACS.