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目的探讨原发性高血压(EH)人群E选择素和C反应蛋白(CRP)与缺血性心电图(IEM)表现的关系。方法对468例EH患者进行心电图检查、E选择素和CRP的检测。结果IEM表现组E选择素(19.9μg/L)与非IEM表现组(19.2μg/L)无区别(P>0.05)。IEM表现组CRP(6.0 mg/L)高于非IEM表现组(5.4 mg/L,P<0.05)。经多因素Logistic回归分析,各E选择素水平对IEM表现的OR值差异均无统计学意义(均P>0.05)。而CRP最高水平组的OR值有统计学意义,多因素调整后的OR为3.28(P<0.05)。结论在EH人群中,血清E选择素水平与EH伴发IEM表现无关,血清CRP与EH伴发IEM表现具有一定的相关性。
Objective To investigate the relationship between E-selectin, C-reactive protein (CRP) and ischemic electrocardiogram (IEM) in essential hypertension (EH). Methods 468 EH patients were examined by electrocardiogram, E-selectin and CRP. Results There was no difference between EEM expression group (19.9μg / L) and non - IEM group (19.2μg / L) (P> 0.05). CRP (6.0 mg / L) was significantly higher in IEM than in non-IEM (5.4 mg / L, P <0.05). After multivariate logistic regression analysis, there was no significant difference in the OR of E-selectin between IEM and EEM (all P> 0.05). The OR of the highest CRP level group was statistically significant, and OR adjusted by multiple factors was 3.28 (P <0.05). Conclusion In EH population, serum E-selectin level has no correlation with EH-associated IEM, and serum CRP has some correlation with EH-associated IEM.