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目的 :了解灯盏花对椎基底动脉性眩晕临床疗效及TCD(经颅彩色多普勒 )改变。方法 :选取椎基底动脉供血不足性眩晕的门急诊及住院患者 6 0例 ,随机选取 30例为灯盏花治疗组 ,另 30例为西比灵治疗的对照组 ,治疗后 1～ 4周复查TCD ,比较用药前后双椎、基底动脉的血流平均流速 (Vm)和收缩峰值 (Vs)的变化情况。结果 :治疗与对照组用药后 1～ 4周复查TCD ,双椎、基底动脉的Vm、Vs值改善程度均有显著性差异 (P<0 .0 1)。结论 :灯盏花注射液可明显改善椎基底动脉流速 ,改善供血从而改善眩晕症状 ,未见明显副作用。
Objective: To understand the clinical efficacy of Breviscapus in vertebrobasilar vertigo and TCD (Transcranial Color Doppler) changes. Methods: Sixty patients from outpatient and emergency department of hospitalized patients with Vertebrobasilar insufficiency dizziness were enrolled. Thirty patients were randomized into the Erigeron breviscapus group and the other 30 patients were treated with xipinine. TCD The changes of mean velocity (Vm) and peak (Vs) of blood flow in both vertebral and basilar arteries were compared before and after treatment. Results: After TCD was examined in 1 to 4 weeks after treatment, the Vm and Vs in both vertebrae and basilar artery were significantly improved (P <0.01). Conclusion: Breviscapine injection can significantly improve vertebrobasilar artery velocity, improve blood supply and improve vertigo symptoms, no obvious side effects.