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诊断标准:①乙醇摄入量≥40g/天,连续5年以上。②B超及或CT有脂肪肝特点。③排除病毒性及药物性肝病。 本组全部为男性,年龄30～70岁,有3例同为一家族。企事业行政干部20例,餐饮业及购销员5例,农民5例。乙醇摄入量最少40g/天,最多220g/天,平均114g/天。饮酒时间10年以内12例,10年以上18例。合并肥胖症21例,合并乙型肝炎病毒标志物阳性6例。因有症状就诊者14例,按出现频度依次为疲劳、上腹胀满、右上腹胀痛、食欲减退、恶心、厌油、黄疸、呕吐等。余16例无症状。查体肝脏肿大20例,轻度触痛8例,均未见蜘蛛痣及肝掌。B超肝脏体积增大,形态饱满,回声增强、后方回声衰减,肝肾回声反差大。实验室检查谷丙转氨酶(ALT)升高(≥30u)及或谷草转氨酶(AST)升高(≥40u)11例,AST/ALT比值>2者9例。碱性磷酸酶(ALP)升高(≥92u)9例,谷氨酰转肽酶(r-GT)升高(≥50u)11例。总胆红素(TBiL)升高(>20.5~mol/L)2例,红细胞平均体积(MCV)升高(>95f1)15例。
Diagnostic criteria: ① ethanol intake ≥ 40g / day for more than 5 years. ② B ultrasound and CT or fatty liver. ③ exclude viral and drug-induced liver disease. This group is all men, aged 30 to 70 years old, 3 cases with the same family. 20 enterprises and administrative cadres, 5 restaurants and sales and sales staff, 5 farmers. Ethanol intake of at least 40g / day, up to 220g / day, an average of 114g / day. Drinking time within 10 years in 12 cases, more than 10 years in 18 cases. 21 cases of obesity combined with hepatitis B virus markers in 6 cases. Due to symptoms of treatment in 14 cases, according to the frequency of occurrence of fatigue, abdominal fullness, right upper quadrant pain, loss of appetite, nausea, tired of oil, jaundice, vomiting. More than 16 cases asymptomatic. Physical examination of liver enlargement in 20 cases, mild tenderness in 8 cases, no spider nevus and liver palms. B ultrasound liver enlargement, full form, enhanced echogenic, rear echo attenuation, liver and kidney echo contrast. Eleven patients with elevated ALT (≥30u) and aspartate aminotransferase (AST) or 9 patients with AST / ALT> 2 were examined in the laboratory. Nine cases had elevated alkaline phosphatase (ALP) (≥92u) and 11 cases had elevated glutamyl transpeptidase (≥50u). Total bilirubin (TBiL) increased (> 20.5 ~ mol / L) in 2 cases, the average volume of red blood cells (MCV) increased (> 95f1) in 15 cases.