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目的探讨上海市延吉社区中老年人群糖调节受损(IGR)的临床特征及其与代谢综合征(MS)的关系。方法对上海市杨浦区延吉社区2228例45～74岁的居民行空腹血糖(FPG)试验,以筛检出的393例IGR者为研究对象,进行问卷调查、体格检查、FPG、糖负荷后2小时血糖测定(2hPG)和血脂检测。结果 IGR人群的平均年龄、体重指数(BMI)、腰围(WC)、腰臀比(WHR)、收缩压(SBP)和甘油三酯(TG)高于血糖正常(NGT)组,差异均有统计学意义(P<0.05)。IGR人群中,全身性肥胖的检出率为17.98%、中心性肥胖检出率为62.36%、血脂异常者为55.62%、符合MS诊断者为53.93%,均高于NGT人群,差异具有统计学意义。结论 IGR人群的MS患病率高于NGT人群,并伴有肥胖、高血压和高甘油三酯的临床特征。
Objective To investigate the clinical features of impaired glucose regulation (IGR) and the relationship with metabolic syndrome (MS) in middle-aged and elderly people in Yanji community, Shanghai. Methods Fasting plasma glucose (FPG) test was conducted in 2228 residents aged 45 ~ 74 years in Yanji Community, Yangpu District, Shanghai. 393 IGR patients were screened for questionnaire, physical examination, FPG, Hourly blood glucose test (2hPG) and lipids test. Results The average age, body mass index (BMI), waist circumference (WHR), systolic blood pressure (SBP) and triglyceride (TG) in IGR group were higher than those in normal glucose group Significance (P <0.05). Among the IGR population, the detection rate of systemic obesity was 17.98%, the incidence of central obesity was 62.36%, the level of dyslipidemia was 55.62%, and the percentage of those with MS diagnosis was 53.93%, which were higher than that of NGT population significance. Conclusion The prevalence of MS in IGR population is higher than that in NGT population, and is associated with clinical features of obesity, hypertension and hypertriglyceridemia.