论文部分内容阅读
慢性阻塞性肺疾病(COPD)气流受限呈进行性发展,主要与肺脏对吸入烟草烟雾等有害气体或颗粒的异常反应有关。许多研究表明,即使是稳定期COPD患者也存在全身炎症反应,表现为C-反应蛋白(CRP)、纤维蛋白原、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)等全身炎症指标升高[1]。COPD患者戒烟后全身炎症反应是否存在可逆性?其可逆程度如何?我们采用前瞻性队列研究的方法,观察稳定期COPD患者戒烟后CRP、纤维蛋白原、TNF-α、IL-6等指标的变化,现报道如下。
Chronic Obstructive Pulmonary Disease (COPD) airflow limited development was progressing, mainly with the lungs on inhalation of tobacco smoke and other harmful gases or particles of the abnormal response. Numerous studies have shown that there is systemic inflammatory response in patients with stable COPD as well, including C-reactive protein (CRP), fibrinogen, tumor necrosis factor-α (TNF-α), interleukin-6 ) And other systemic inflammatory indicators increased [1]. COPD patients after smoking cessation of systemic inflammatory response is reversible? How its reversibility? We use a prospective cohort study to observe the steady-state COPD patients quit smoking CRP, fibrinogen, TNF-α, IL-6 and other indicators of change Now reported as follows.