【摘 要】
：
The strained cyclopropane and/or cyclobutane subunits occurred in many complex natural products including terpenoids, steroids and alkaloids. Natural products w
【机 构】
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Shanghai Institute of Materia Medica, Chinese Academy of Sciences,
【出 处】
：
Science China(Chemistry)
论文部分内容阅读
The strained cyclopropane and/or cyclobutane subunits occurred in many complex natural products including terpenoids, steroids and alkaloids. Natural products with cyclopropane and/or cyclobutane motifs not only furnished fascinating structures, but also exhibited versatile biological activities, such as cytotoxic, anti-HIV, antimicrobial, antiviral, and immunosuppressive effects. This review covered a large array of structurally unique natural products with strained cyclopropane and/or cyclobutane motifs and summarized their structural features, distributions, biological activities, as well as biogenetic considerations.
The strained cyclopropane and / or cyclobutane subunits occurred in many complex natural products including terpenoids, steroids and alkaloids. Natural products with cyclopropane and / or cyclobutane motif not only furnished fascinating structures, but also versatile biological activities, such as cytotoxic, anti-HIV , antimicrobial, antiviral, and immunosuppressive effects. This review covers a large array of structurally unique natural products with strained cyclopropane and / or cyclobutane motifs and summarized their structural features, distributions, biological activities, as well as biogenetic considerations.
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