Impact of chronic exposure to bevacizumab on EpCAM-based detection of circulating tumor cells

• 作 者: Chiara Nicolazzo Isabella Mass
• 机 构: DipartimentodiMedicinaMolecolare,DipartimentodiMedicinaSperimentale
• 出 处: 中国癌症研究：英文版
• 发表日期: 2015年5期
• 关键词: 细胞检测 肿瘤细胞 单抗 循环 慢性 细胞粘附分子 CTCS 阳性 Circulating tumor cells （CTCs） epithelial cell

Background:Circulating tumor cells(CTCs) are often undetected through the immunomagnetic epithelial cell adhesion molecule(EpCAM)-based CellSearch~ System in breast and colorectal cancer(CRC)patients treated with bevacizumab(BEV),where low CTC numbers ha