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目的观察布地奈德混悬液联合硫酸特布他林雾化液治疗先天性心脏病合并毛细支气管炎的临床效果。方法选择在医院接受治疗的患有先天性心脏病合并毛细支气管炎的患者100例作为研究对象,按照入院时间先后依次编号,以单号患者为试验组,双号患者为对照组。试验组50例患者给予布地奈德混悬液联合硫酸特布他林雾化液治疗,对照组50例患者接受常规治疗。比较2组临床疗效、症状(气促、咳嗽、湿啰音)改善时间、住院时间以及2组患者经雾化吸入治疗时,对呼吸、血压、血氧饱和度以及心率的影响情况。结果试验组患儿的总有效率为98.00%明显高于对照组的64.00%,差异有统计学意义(P<0.05)。试验组患儿的气促稳定时间、咳嗽消失时间、湿啰音消失时间以及住院时间均显著短于对照组,差异均有统计学意义(P<0.05)。2组患儿的血压、呼吸频率、血氧饱和度以及心率比较,差异无统计学意义(P>0.05)。结论对先天性心脏病合并毛细支气管炎患者应用布地奈德混悬液联合硫酸特布他林雾化液治疗效果显著,安全有效的消除炎性反应,对心功能起到较好的保护,值得在临床广泛推广应用。
Objective To observe the clinical efficacy of budesonide suspension combined with terbutaline sulphate nebulizer in the treatment of congenital heart disease complicated with bronchiolitis. Methods 100 patients with congenital heart disease complicated with bronchiolitis who were treated in hospital were selected as research objects, numbered in sequence according to admission time, single number patients as test group and double number patients as control group. Fifty patients in the experimental group were given budesonide suspension combined with terbutaline sulphate nebulization solution, and 50 patients in the control group received routine treatment. The clinical effects, the improvement of symptoms (shortness of breath, cough, wet rales), the length of hospital stay and the effects of inhalation, blood pressure, oxygen saturation and heart rate on the two groups were compared. Results The total effective rate of the experimental group was 98.00%, which was significantly higher than that of the control group (64.00%), the difference was statistically significant (P <0.05). The time of stoichiometry, disappearance of cough, disappearance of wet rales and hospital stay in the experimental group were significantly shorter than those in the control group (P <0.05). There was no significant difference in blood pressure, respiratory rate, oxygen saturation and heart rate between the two groups (P> 0.05). Conclusion The treatment of congenital heart disease combined with bronchiolitis patients with budesonide suspension combined with terbutaline sulfate nebulizer significant effect, safe and effective elimination of inflammatory reactions, heart function play a better protection, it is worth Widely used in clinical practice.