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目的:探讨人巨细胞病毒感染在各种常见疾病和各年龄段中的动态分布。方法:对2005-2012年浙江大学医学院附属儿童医院门诊和住院的5 721例儿童进行人巨细胞病毒抗体检测,统计不同病种及年龄段人巨细胞病毒感染阳性率。结果:在各种儿童常见疾病中,噬血细胞综合症、各种原因引起的肝脾肿大、何杰金氏病、肝功能异常、血小板减少等疾病巨细胞病毒感染阳性率最高。儿童1~3岁时,最容易感染巨细胞病毒。结论:在临床各类疾病诊断治疗过程中,处于1~3岁儿童或有相应症状的患者,须尽早检测巨细胞病毒抗体,以减少儿童各脏器的损害。
Objective: To investigate the dynamic distribution of human cytomegalovirus infection in various common diseases and all ages. Methods: From 2005 to 2012, 5 721 children from outpatient and inpatient department of Children’s Hospital Affiliated to Zhejiang University Medical College were tested for cytomegalovirus antibody. The positive rates of cytomegalovirus infection in different disease types and age groups were calculated. Results: Among the common diseases in children, hemophagocytic syndrome, hepatosplenomegaly, Hodgkin’s disease, abnormal liver function, thrombocytopenia and other diseases caused by various causes had the highest positive rate of CMV infection. Children 1 to 3 years old, most likely to be infected with cytomegalovirus. Conclusion: In the clinical diagnosis and treatment of various diseases, in children aged 1-3 or patients with corresponding symptoms, as soon as possible detection of cytomegalovirus antibodies to reduce the damage of various organs of children.