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OBJECTIVE To investigate the rehabilitation e. ect of systematic exercise on breast cancer patients a er adjuvant chemotherapy.METHODS One hundred and ten subjects were randomly divided into 2 groups. The patients in the control group received original exercise. The others in the intervention group received systematic exercise including aerobics and 24 postures of Taichi for 4 months besides the original exercise.RESULTS After the systematic exercise, the limb muscle strength, maximal oxygen uptake and lung capacity of the patients in intervention group were increased compared with those before the systematic exercise (P < 0.05). The lung capacity of patients in the intervention group was signifi cantly increased than the control group after the exercise (P < 0.05). The body mass index (BMI),the ratio of waist and hip (WHR) of the patients in intervention group were decreased compared with those before the systematic exercise (P < 0.05). The bone mineral density of control group was decreased comparing with pre-exercise (P < 0.05), but there was no signifi cant di. erence in the intervention group between pre-exercise and pro-exercise (P > 0.05). There was no significant dierence in the quality of life between the 2 groups a er the systematic exercise (P > 0.05).CONCLUSION Systematic exercise can not only promote the restoration of limb function in patients with breast cancer after treatments, but also improve pulmonary function of the patients and lower the BMI and WHR of the patients. Systematic exercisecan improve the outcomes of overall rehabilitation.