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目的比较并评价头孢他美酯与头孢克肟治疗小儿细菌性腹泻病有效性、安全性和药物经济学意义。方法将106例小儿细菌性腹泻病病例,按治疗方案的不同分为头孢他美酯组和头孢克肟组进行治疗,利用药物经济学成本-效果分析方法,对这两种治疗方法的疗效和成本进行评价。结果两组治疗方案的显效率分别为73.58%和64.15%,总有效率分别为96.23%和92.54%,两组疗效比较无显著性差异(P>0.05),但头孢他美酯组的成本-效果比低于头孢克肟组。结论头孢他美酯治疗小儿细菌性腹泻病的经济效果优于头孢克肟。
Objective To compare and evaluate the efficacy, safety and pharmacological significance of cefetamet and cefixime in the treatment of pediatric bacterial diarrhea. Methods A total of 106 cases of bacterial diarrhea in children were divided into cefetamet pivoxil group and cefixime group according to the different treatment regimens. The efficacy and cost-effectiveness analysis methods were used to analyze the efficacy and safety of the two treatment methods Cost evaluation. Results The effective rates of the two treatment regimens were 73.58% and 64.15%, respectively. The total effective rates were 96.23% and 92.54% respectively. There was no significant difference between the two groups (P> 0.05) The effect is lower than the cefixime group. Conclusions Ceftazidime is superior to cefixime in the treatment of children with bacterial diarrhea.