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目的：了解和掌握准分子激光角膜表面切削术（PRK）后发生角膜混浊（Haze）情况并评价其相关影响因素。方法：将应用NIDEKEC－5000型扫描型准分子激光治疗的3896只眼发生2级以上Haze者做为分析对象并进行统计学处理。结果：术后两年随访发现：术后曾发生明显角膜混浊者31只眼（0.79％），平均等效球镜-7.34±1.14，散光1.52±1.35。96.77%为双眼同时发生，70.96%伴有屈光度的回退、对药物治疗敏感者51.61％，余需手术治疗。结论：PRK术后角膜混浊发生具有一定临床特点：多发生于年轻患者；以男性为多；以双眼同时发生居多;且大部分伴有屈光度回退并与术前屈光度和散光度成正相关，
Objective: To understand and master the corneal haze after excimer laser keratoplasty (PRK) and evaluate its related factors. METHODS: 3896 eyes with NIDEKEC-5000 scanning excimer laser were treated with Haze level 2 or higher and analyzed statistically. Results: Two years after operation, there were 31 eyes (0.79%) with obvious corneal opacity, mean spherical equivalent of -7.34 ± 1.14, astigmatism of 1.52 ± 1.35.96.77%, simultaneous occurrence of both eyes and 70.96% with corneal opacity Refractive degree of regression, 51.61% sensitive to drug treatment, the remaining need for surgical treatment. Conclusions: Corneal opacification after PRK has some clinical features: Occurred in young patients; mostly in men; mostly in both eyes; and most are associated with refractive regression and preoperative refractive power and astigmatism was positively correlated,