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目的 :观察HIV的发展过程中 ,感染者血清HIV抗体水平的变化及特异性抗体丢失情况。方法 :对HIV感染者发病前后血清内HIV抗体滴度及其抗体膜带进行对比。结果 :随着病程的发展 ,所观察的 3 0例HIV感染者中 ,转变为AIDS患者后均有HIV抗体水平下降及HIV特异性抗体丢失。结论 :AIDS患者发病前后HIV抗体水平明显下降 ,HIV特异性抗体的种类逐渐减少 ,以抗 p17抗体丢失为常见。
OBJECTIVE: To observe the changes of serum HIV antibody levels and the loss of specific antibodies during the development of HIV. Methods: The HIV antibody titers and their antibody membrane bands in serum before and after HIV infection were compared. Results: With the development of the course of disease, among the 30 cases of HIV-infected patients observed, the level of HIV antibody and the loss of HIV-specific antibody were all decreased after the AIDS patients were converted. Conclusion: The level of HIV antibody in AIDS patients before and after the onset of AIDS decreased significantly. The types of HIV-specific antibodies gradually decreased, and the loss of anti-p17 antibody was common.