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目的:研究肌内黏液瘤的临床病理学特点,探讨其诊断和鉴别诊断。方法:对2例肌内粘液瘤进行临床病理分析,并应用VIM、CD34、SMA、S-100进行免疫组化染色。结果:肿瘤有粘滑外观,镜下见肿瘤由丰富的粘液样基质及稀少的星芒状、短梭形细胞构成,血管结构稀少,部分区域可见浸润周围骨骼肌;免疫组化Vim(2例均阳性),CD34(其中1例阳性),S-100、SMA均为阴性。结论:肌内黏液瘤是少见的来源不明的良性软组织肿瘤,可以根据形态学和免疫组化加以诊断,需与一些肿瘤做鉴别诊断;完整切除,预后良好。
Objective: To study the clinicopathological features of intramuscular myxoma and discuss its diagnosis and differential diagnosis. Methods: Two cases of intramuscular myxoma were analyzed by clinicopathology and immunohistochemical staining was performed with VIM, CD34, SMA and S-100. RESULTS: The tumor had a sticky-slip appearance. Under the microscope, the tumor consisted of abundant mucin-like stroma and sparse stellate and short spindle cells. The vascular structure was sparse. Infiltration of peripheral skeletal muscle was seen in some areas; immunohistochemistry Vim (2 cases) All were positive), CD34 (one case was positive), S-100, SMA were all negative. Conclusion: Intramuscular myxoma is a rare benign soft tissue tumor of unknown origin. It can be diagnosed according to morphology and immunohistochemistry. It needs to be differentiated from some tumors. Complete resection has a good prognosis.