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瘦素 (ｌｅｐｔｉｎ)是由脂肪组织分泌的 14 6个氨基酸的激素 ,其前体是 16 7个氨基酸的蛋白质 ,Ｎ -端 2 1肽是信号肽[1 ] 。ｌｅｐｔｉｎ进入血循环后与下丘脑的特异性受体结合 ,通过一系列神经和体液因素调整体脂库的大小 ,最终控制体重相对恒定[2 ] 。ｌｅｐｔｉｎ与肥胖、
Leptin is a 14-amino acid hormone secreted by adipose tissue. Its precursor is a protein of 167 amino acids. The N-terminal 21 peptide is a signal peptide [1]. Leptin enters the blood circulation and binds to specific receptors in the hypothalamus, adjusting the size of the body fat bank through a series of neurological and humoral factors, eventually controlling the body weight relatively constant [2]. leptin and obesity,