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将人用流产药物利洛司酮和米非司酮用于早期妊娠(孕期26~32d)猕猴使之流产,利用放射免疫测定法(RIA)测定给药组(12只)及阴性对照组(4只)流产前后的血清孕酮水平。结果显示流产前后孕酮水平差异非常明显(P<0.01),因此测定血孕酮含量可作为判断用药猕猴是否流产的一个指标。
The human abortion drug lilopristone and mifepristone used for early pregnancy (26 ~ 32d gestational age macaque abortion, the use of radioimmunoassay (RIA) measured the administration group (12) and the negative control group 4) serum progesterone levels before and after abortion. The results showed that progesterone levels before and after abortion were significantly different (P <0.01), so the determination of blood progesterone content can be used as a marker to determine whether abortion macaque an indicator.