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目的:探讨老年脑梗死患者颈动脉粥样硬化斑块超声特征与血脂的关系。方法:应用彩色多普勒超声仪对120例老年脑梗死患者的颈动脉进行检测,根据检测结果,将患者分为斑块组和无斑块组,分别检测总胆固醇(TC)、甘油三脂(TG)、高密度蛋白(HDL-C)、低密度脂蛋白(LDL-C)、载脂蛋白A(apoA)、载蛋白B(apoB)、脂蛋白α(LPa)。观察颈动脉粥样硬化斑块的发生与血脂的关系。结果:斑块组TG、LDL-C、apoB、LPα浓度显著高于无斑块组(P<0.05),Logistic多元回归分析显示,颈动脉粥样硬化程度与LDL-C、LPα呈显著正相关(P<0.05)。结论:LDL-C、LPα增高是颈动脉粥样硬化斑块形成的主要因素和诊疗的观察指标,超声检测颈动脉粥样斑块再结合血脂检测,对于脑血管疾病的预防、早期诊断、指导治疗以及观察疗效具有一定的价值。
Objective: To investigate the relationship between the ultrasonic features of carotid atherosclerotic plaques and serum lipids in elderly patients with cerebral infarction. Methods: The carotid arteries of 120 elderly patients with cerebral infarction were detected by color Doppler ultrasound. According to the results of the test, the patients were divided into plaque group and non-plaque group. Total cholesterol (TC), triglyceride TG, HDL-C, LDL-C, apoA, apoB and LPa were measured. To observe the occurrence of carotid atherosclerosis plaque and the relationship between blood lipids. Results: The levels of TG, LDL-C, apoB and LPα in plaque group were significantly higher than those in plaque group (P <0.05). Logistic multiple regression analysis showed that carotid atherosclerosis was positively correlated with LDL-C and LPα (P <0.05). Conclusion: Increased LDL-C and LPα are the main factors in the formation of carotid atherosclerosis plaque and the observation and treatment of carotid atherosclerotic plaque. Ultrasound detection of carotid atherosclerotic plaque re-incorporation of lipids, prevention, early diagnosis and guidance of cerebrovascular disease Treatment and observation of efficacy has some value.