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血清和血浆中地高辛浓度的测定已用于临床急救15年了,但对测定的价值仍有怀疑.血清地高辛浓度与中毒体征缺少联系而未引起往意。许多研究发现治疗量与中毒量有较多重叠,是由于对地高辛的敏感性因素所致,如心肌病和电解质失衡等,这些提示来血和测定的标准化将增加药物测定的可信性。最近在门诊已注意到测定地高辛浓度时采血的标准化问题。并发现日常的运动可以减少血清中地高辛的浓度,因为地高辛可以结合到运动的骨骼肌上.在门诊病人取血测定地高辛浓度时,有必要先
The determination of digoxin concentrations in serum and plasma has been used clinically for first aid for 15 years, but there is still doubt about the value of the assay. Serum digoxin concentrations are associated with lack of signs of poisoning. Many studies have found that the amount of treatment and poisoning overlap more because of the sensitivity to digoxin factors, such as cardiomyopathy and electrolyte imbalance, which prompted the blood and the standardization of the test will increase the credibility of the drug assay . Recent outpatient visits have noted the standardization of blood sampling for the determination of digoxin concentrations. And found that daily exercise can reduce the concentration of digoxin in serum, because digoxin can be combined with the exercise of skeletal muscle in blood outpatient determination of digoxin concentrations, it is necessary