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目的分析不同促排卵方案对多囊卵巢综合征(PCOS)患者体外受精-胚胎移植(IVF-ET)周期治疗结果的影响。方法回顾性分析2012年1月至2013年1月行IVF长方案助孕治疗的PCOS患者共127取卵周期,按Gn用量分为A组:恒量方案组(共89周期)和B组:剂量递增方案组(共38周期),对治疗中及治疗结局相关因素进行比较分析。结果恒量方案组Gn用量及Gn天数显著低于递增方案组,HCG日>19mm卵泡数、穿刺卵泡数、获卵总数、周期取消率均显著高于递增方案组,两组内复融周期妊娠率比新鲜周期均显著增加;其余各项差异无统计学意义。结论恒量方案组可减少用药量,提高获卵数。PCOS患者可考虑新鲜周期全胚冷冻,复融周期移植方案降低OHSS发生率,提高妊娠率。
Objective To analyze the effect of different ovulation induction regimens on the outcome of IVF-ET in patients with polycystic ovary syndrome (PCOS). Methods A total of 127 ovulation cycles of PCOS patients undergoing long-term IVF convalescent treatment from January 2012 to January 2013 were retrospectively analyzed. Group A consisted of a constant-dose regimen (a total of 89 cycles) and a dose-dependent Increasing the program group (a total of 38 cycles), the treatment and treatment-related factors were compared. Results The dosage of Gn and the number of Gn days in the constant regimen group were significantly lower than those in the incremental regimen group. The number of follicles> 19mm, the number of follicles punctured, the total number of oocytes retrieved and the cycle revocation rate were significantly higher in HC group than in increasing regimen group. Than the fresh cycle were significantly increased; the remaining differences were not statistically significant. Conclusions The constant dose group can reduce the dosage and increase the number of oocytes retrieved. PCOS patients can consider fresh cycle whole embryo freezing, cycloplegic cycle transplantation plan to reduce the incidence of OHSS and improve pregnancy rate.