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目的探讨影响三维适形放疗(3D-CRT)以及调强放疗(IMRT)治疗食管癌患者预后的相关因素。方法选取85例食管癌患者作为研究对象,其中59例患者接受3D-CRT,26例患者接受IMRT。治疗结束后对患者进行随访。结果单因素分析显示,性别、年龄、体质指数(BMI)与食管癌患者预后无相关性(P>0.05);病变长度、食管肿瘤最大直径、大体肿瘤体积(GTV)、N分期、T分期、联合化疗与食管癌患者预后相关(P<0.05)。多因素分析显示,GTV、N分期、联合化疗是影响3D-CRT以及IMRT治疗食管癌预后的独立相关因素(P<0.05)。结论根据相关因素分析结果,采取相应的措施可改善3D-CRT以及IMRT治疗食管癌的预后。
Objective To investigate the factors that affect the prognosis of esophageal cancer patients undergoing three-dimensional conformal radiotherapy (3D-CRT) and intensity modulated radiotherapy (IMRT). Methods Eighty-five patients with esophageal cancer were enrolled in this study. 59 patients underwent 3D-CRT and 26 received IMRT. Patients were followed up after treatment. Results Univariate analysis showed no correlation between sex, age, body mass index (BMI) and the prognosis of patients with esophageal cancer (P> 0.05). The length of lesion, the maximum diameter of esophageal tumor, gross tumor volume (GTV), N stage, T stage, The combination of chemotherapy and prognosis of patients with esophageal cancer (P <0.05). Multivariate analysis showed that GTV, N staging and combination chemotherapy were the independent factors influencing prognosis of 3D-CRT and IMRT for esophageal cancer (P <0.05). Conclusion According to the results of related factors analysis, the corresponding measures can be taken to improve the prognosis of esophageal cancer by 3D-CRT and IMRT.