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目的探讨分析老年肺源性心脏病(肺心病)应用丹参酮ⅡA磺酸钠注射液的治疗效果,以丰富临床治疗经验。方法 144例肺心病老年患者,随机分为对照组和观察组,各72例。对照组老年患者采取常规治疗,观察组老年患者则在此基础上采取丹参酮ⅡA磺酸钠注射液治疗。对比两组老年患者的疗效,并且对比治疗之后D-二聚体、纤维蛋白原和肺动脉收缩压等指标。结果观察组患者的治疗总有效率为97.2%,显著优于对照组的76.4%,差异具有统计学意义(P<0.05)。与治疗前对比,观察组老年患者治疗后D-二聚体、纤维蛋白原和肺动脉收缩压显著降低,差异具有统计学意义(P<0.05)。结论使用丹参酮ⅡA磺酸钠注射液能够有效的减轻肺动脉压,改善老年患者在加重期时血栓的状况,临床治疗效果显著,值得在临床中进一步推广应用。
Objective To investigate the treatment of senile pulmonary heart disease (pulmonary heart disease) with tanshinone Ⅱ A sodium sulfonate injection in order to enrich clinical experience. Methods A total of 144 elderly patients with pulmonary heart disease were randomly divided into control group and observation group, with 72 cases in each group. The control group of elderly patients to take conventional treatment, the elderly were observed in this group on the basis of tanshinone Ⅱ A sodium sulfonate treatment. Efficacy of two groups of elderly patients was compared, and D-dimer, fibrinogen and pulmonary artery systolic blood pressure were compared after treatment. Results The total effective rate of observation group was 97.2%, which was significantly better than 76.4% of control group, the difference was statistically significant (P <0.05). Compared with those before treatment, the systolic blood pressure of D-dimer, fibrinogen and pulmonary artery in the observation group were significantly decreased after treatment, the difference was statistically significant (P <0.05). Conclusion Sodium tanshinone Ⅱ A sulfonate injection can effectively relieve pulmonary arterial pressure and improve the status of thrombosis in elderly patients during exacerbation. The clinical effect is significant and worthy of further application in clinic.