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[目的]观察金水宝联合依那普利治疗糖尿病肾病疗效。[方法]使用随机平行对照方法,将44例门诊患者按随机数字表法随机分为两组。对照组22例依那普利,10mg/次,1次/d,口服。治疗组22例金水宝,3粒/次,3次/d、口服依那普利治疗同对照组。治疗30d为1疗程。观测临床症状、24h尿微量白蛋白、血糖、血压、血常规、血生化、肝功能、不良反应。连续治疗3个疗程,判定疗效。[结果]治疗组显效11例,有效10例,无效1例,总有效率95.45%。对照组显效5例,有效6例,无效11例,总有效率50.00%。治疗组疗效优于对照组(P<0.05)。治疗前、后24h尿微量白蛋白治疗组优于对照组(P<0.05)。[结论]金水宝联合依那普利治疗糖尿病肾病效果显著,值得推广。
[Objective] To observe the therapeutic effect of Jinshuibao enalapril on diabetic nephropathy. [Methods] Using randomized parallel control method, 44 outpatients were randomly divided into two groups according to random number table method. Control group, 22 cases of enalapril, 10mg / time, 1 / d, orally. Treatment group, 22 cases of Jin-Bao, 3 capsules / time, 3 times / d, oral enalapril treatment with the control group. Treatment for 30d for a course of treatment. Observations of clinical symptoms, 24h urinary albumin, blood glucose, blood pressure, blood, blood biochemistry, liver function, adverse reactions. Continuous treatment of three courses to determine the efficacy. [Results] The treatment group was markedly effective in 11 cases, effective in 10 cases, ineffective in 1 case, the total effective rate was 95.45%. The control group markedly effective in 5 cases, effective in 6 cases, ineffective in 11 cases, the total effective rate was 50.00%. The treatment group was better than the control group (P <0.05). 24h urine microalbuminuria treatment group was better than the control group before and after treatment (P <0.05). [Conclusion] Jinshuibao combined enalapril treatment of diabetic nephropathy effect is significant, it is worth promoting.