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在儿童肾移植中使用皮质醇激素可以引起儿童生长延迟,因此在儿童肾移植中停用类固醇激素是必要的。L·Ghio等对29名儿童肾移植受者有选择地停用类固醇激素进行了前瞻性研究。免疫抑制剂方案:术前及术后头三天静脉给CSA5mg/kg/d,之后改为口服17mg/kg/d,术后头一个月每2周减2mg/kg,一个月后每月减2mg/kg,至术后第三个月底减至11mg/kg/d,术后第96天起以10mg/kg/d维持。调节全血CSA浓度头一个月在400~800ng/ml(RIA法),之后为250~350ng/ml。甲基强的松龙(MP)术中给250~500mg,其后2天静脉给160mg及80mg,然后口服
The use of cortisol in children with kidney transplants can cause delays in the growth of children, and steroid steroids are necessary in childhood kidney transplants. L · Ghio and other 29 children with renal transplant recipients selectively steroid hormone were prospectively studied. Immunosuppressant regimen: CSA5mg / kg / d was administered intravenously in the first three days before and after the operation, then to 17mg / kg / d orally. The first month after operation was reduced by 2mg / kg every two weeks, 2 mg / kg until the end of the third month to 11 mg / kg / d and from 96 days after surgery to 10 mg / kg / d. Regulated whole blood CSA concentration in the first month at 400 ~ 800ng / ml (RIA method), followed by 250 ~ 350ng / ml. Methylprednisolone (MP) intraoperative to 250 ~ 500mg, followed by 2 days intravenous 160mg and 80mg, and then orally