Novel MSX1 variants identified in families with nonsyndromic oligodontia

• 作 者: Jinglei Zheng Miao Yu Haochen Liu Tao Cai Hailan Feng Yang Liu Dong Han
• 机 构: DepartmentofProsthodontics,NationalInstituteofDentalandCraniofacialResearch
• 出 处: 国际口腔科学杂志:英文版
• 发表日期: 2021年1期
• 基金项目: supported by the National Natural Science Foundation of China(81970902,81771054,and 81600846).

The goal of this study was to identify MSX1 gene variants in multiple Chinese families with nonsyndromic oligodontia and analyse the functional influence of these variants.Whole-exome sequencing(WES)and Sanger sequencing were performed to identify the cau