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目的探讨稳定性心绞痛采用尼可地尔治疗效果。方法选取稳定性心绞痛患者100例,均为郑州市第一人民医院内科2014年10月至2015年10月收治,采用数字表抽取法随机分组,就常规药物治疗(对照组,n=50)与加用尼可地尔治疗(观察组,n=50)效果展开对比。结果观察组选取的稳定性心绞痛患者临床总有效率经统计为96%,明显高于对照组74%,有显著统计学差异(P<0.05)。观察组在用药期间胃部轻微不适2例,改餐后服用,不适症状消失;对照组腹部不适3例,恶心、呕吐2例,药物坚持应用,3~4d后缓解,均无严重不良反应。结论针对临床收治的稳定性心绞痛病例,在常规药物治疗的同时,取尼可地尔加服,可促临床症状消除,增强用药效果,且未增加用药不良反应,有较高推广应用价值。
Objective To investigate the effect of nicorandil in patients with stable angina pectoris. Methods 100 patients with stable angina pectoris were enrolled in the First People’s Hospital of Zhengzhou City from October 2014 to October 2015. The patients were randomly divided into three groups according to the routine medication (control group, n = 50) Add nicorandil treatment (observation group, n = 50) the effect of contrast. Results The total clinical effective rate of patients with stable angina pectoris selected by the observation group was statistically significant at 96%, significantly higher than 74% in the control group (P <0.05). In the observation group, gastric discomfort was observed in 2 cases during the treatment period. After the meal was taken, the symptoms disappeared. In the control group, 3 cases of discomfort in the abdomen, nausea and vomiting were observed in 2 cases. The drug was insisted on and was relieved after 3 ~ 4 days without serious adverse reactions. Conclusion For the patients with stable angina pectoris admitted to our hospital, we can take nicorandil plus traditional Chinese medicine to relieve clinical symptoms and enhance the effect of medication without increasing adverse drug reactions, which is of great value in popularization and application.