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目的:探讨终末期肿瘤恶液质患者营养治疗临床效果。方法:选取2014年1月~2015年12月在我院采取肠外营养支持治疗的131例晚期肿瘤恶液质患者进行分析,观察并比较患者营养支持治疗前后体力状况评分以及不良反应发生情况。结果:所有患者经过营养支持治疗后,其ECOG平均评分为(2.0±1.0)分,较治疗前(3.7±0.8)分,明显减少,治疗前后比较差异具有统计学意义(P<0.05);患者腹泻1例、呕吐恶心1例,未见严重不良反应;对终末期不同肿瘤类型恶液质患者进行分类,同时分析其ECOG评分,发现营养支持治疗对食管癌、乳腺癌和大肠癌的治疗效果较好,而对于胃癌和肺癌的治疗效果较低。结论:终末期肿瘤恶液质患者采取营养支持治疗有助于改善其生活自理能力以及提高预后生活质量,且未见严重不良反应,该方法安全可靠。
Objective: To investigate the clinical effect of nutritional therapy in patients with end-stage tumor cachexia. Methods: One hundred and thirty-one patients with advanced neoplasms of malignant tumor treated with parenteral nutrition support in our hospital from January 2014 to December 2015 were selected for analysis. Physical status scores and adverse reactions before and after nutrition support were observed and compared. Results: The average ECOG score of all patients after nutritional support was (2.0 ± 1.0) points, which was significantly lower than that before treatment (3.7 ± 0.8) points, with significant difference before and after treatment (P <0.05). Patients 1 case of diarrhea and 1 case of vomiting and nausea. No serious adverse reactions were observed. The patients with different types of neoplasms in the end stage were classified, and their ECOG scores were also analyzed. The therapeutic effects of nutritional support on esophageal cancer, breast cancer and colorectal cancer were found Better, while for gastric and lung cancer treatment less effective. Conclusion: The nutritional supportive treatment of patients with end-stage tumor cachexia is helpful to improve the self-care ability of life and improve the quality of life of prognosis, and no serious adverse reactions, the method is safe and reliable.