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目的:分析和探讨抗感染药物不良反应/事件报告相关因素及其预防措施。方法:选取2013年1月—2015年1月间收集的500例抗感染药物不良反应/事件的报告,采用回顾性分析方法分析抗感染药物不良反应/事件报告相关因素及其预防措施。结果:抗感染药物不良反应/事件报告中儿童患者100例为20.00%;50岁以上的患者300例为60.00%;其使用方法最多的为静脉滴注450例为90.00%;种类以头孢菌素类和氟喹诺酮类药物为主,所占的比率分别为45.80%(229/500)和23.20%(116/500);涉及皮肤和皮肤附件等为24.20%(121/500),消化系统为106例(21.20%),呼吸系统为94例(18.80%)。结论:严密监测抗感染药物不良反应/事件的发生,加强抗感染药物的使用管理,对于避免出现不良反应/事件具有重要的意义。
Objective: To analyze and discuss the related factors and preventive measures of ADR / EV report. Methods: A total of 500 adverse drug reactions / events collected during January 2013-January 2015 were collected. Retrospective analysis methods were used to analyze the related factors and preventive measures of ADR / EV reports. Results: 100.00% of pediatric patients in adverse drug reaction / incident reports were 20.00%, 300% of patients over 50 years old were 60.00%, 450% of them were used as 90.00% And fluoroquinolones accounted for 45.80% (229/500) and 23.20% (116/500), respectively. Skin and skin attachments accounted for 24.20% (121/500) and the digestive system was 106 Cases (21.20%), respiratory system was 94 cases (18.80%). CONCLUSIONS: Closely monitoring the incidence of adverse reactions / events of anti-infective drugs and strengthening the management of the use of anti-infective drugs are of great significance in avoiding adverse reactions / events.