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测定45例脑血栓患者血胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C),低密度脂蛋白胆固醇(LDL-C)、极低密度脂蛋白胆固醇(VLDL-C)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)、ApoA1/ApoB比值,LDL-C/HDL-C比值与对照组比较,脑血栓患者TC、TG、LDL-C、VLDL-C、ApoB、LDL-C/HDL-C比值较对照组显著升高P<0.01~0.001,HDL-C、ApoA1/ApoB比值较对照组显著降低P<0.001,ApoA1脑血栓患者与对照组无显著差异P>0.05。结果提示:LDL-C、VLDL-C、ApoB、LDL-C/HDL-C比值增高HDL-C、ApoA1/ApoB比值降低均是诱发脑血栓形成的重要危险因素,ApoA1/ApoB比值显著降低,LDL-C/HDL-C比值显著升高均是诱发脑血栓形成的显著危险因素。
The serum levels of TC, TG, HDL-C, LDL-C, VLDL-C were determined in 45 patients with cerebral thrombosis. C, ApoA1, ApoB, ApoA1 / ApoB and LDL-C / HDL-C in patients with cerebral thrombosis were significantly higher than those in control group C, ApoB and LDL-C / HDL-C were significantly higher than those in the control group (P <0.01-0.001). The ratios of HDL-C and ApoA1 / ApoB were significantly lower than those in the control group No significant difference between patients and control group P> 0.05. The results suggested that the decrease of HDL-C, ApoA1 / ApoB ratio were all the significant risk factors of cerebral thrombosis, and the ratio of ApoA1 / ApoB was significantly lower than that of LDL-C, VLDL-C, ApoB and LDL-C / Significantly increased C / HDL-C ratio were all significant risk factors for inducing cerebral thrombosis.