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研究显示,相对于不饮酒者和重度饮酒者而言,中度饮酒者心血管疾病死亡率较低,但是没有相关的随机性试验支持这一论点。虽然大部分的观察性研究揭示了引发心脏病的主要危险因素,但是心血管疾病仍独立地与其他的能够解释中度饮酒利于心血管疾病的因素相关。在中度饮酒者和不饮酒者中进行心血管疾病的流行风险因素和潜在的混淆因子的评定研究,中度饮酒者定义为2次/d饮酒的男性,或1次/d饮酒的女性。在调整了年龄和性别后,根据人口统计、社会、行为、健康保健评定及健康相关条件等因素来看,不饮酒者与心血管疾病死亡率的增加之间具有更为特异性相关。在所评定的30个心血管疾病相关风险因素中,在不饮酒者有27个显著存在。在复合型风险因素中,那些高风险因素更亲睐不饮酒者,排除那些身体健康状况较差或具有心血管疾病患病史的人对结果没有影响。这些发现显示,中度酒精摄入对于心血管疾病部分的或全部的明显的防护影响可以归于其他因素或未计量的混杂因素。由于有关中度饮酒对健康影响的非随机研究的解释有局限性,故结论应当谨慎,特别是因为在美国过度饮酒已经引发了健康危害。
Studies have shown that cardiovascular deaths among moderate drinkers are lower relative to non-drinkers and heavy drinkers, but no relevant randomized trial supports this argument. Although the majority of observational studies have uncovered the major risk factors for heart disease, cardiovascular disease independently correlates with other factors that can explain moderate alcohol consumption in favor of cardiovascular disease. Study of risk factors and potential confounding factors for cardiovascular disease in moderate drinkers and non-drinkers. Moderate drinkers were defined as men who drank twice a day or women who drank once a day. After adjustment for age and gender, non-drinkers have a more specific correlation with increases in cardiovascular mortality based on factors such as demographics, social, behavioral, health care assessments, and health-related conditions. Of the 30 cardiovascular risk-related risk factors assessed, there were 27 significant non-drinkers. Of the composite risk factors, those who are more risk-averse prefer non-drinkers, and those who exclude poor health or have a history of cardiovascular disease have no effect on outcomes. These findings show that the significant protective effect of moderate alcohol intake on some or all of the cardiovascular disease may be attributed to other factors or unmetered confounding factors. Due to limitations in the interpretation of non-randomized studies on the health effects of moderate alcohol consumption, conclusions should be taken with caution, especially since excessive alcohol consumption in the United States has caused a health hazard.