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根据对山区、半山区、平原、沿海几个调查点四万人的甲状腺检查和尿碘、水碘的分析,揭示了从“低碘”、“中碘”到“高碘”地区的碘和人群中甲状腺肿流行的关系:①尿碘在50 μg/g肌酐,水碘在5 μg/l以下时,碘越少甲状腺肿流行率越高;②尿碘从50 μg/g肌酐,到400 μg/g肌酐,水碘从5 μg/l到40 μg/l,甲状腺肿流行率降到最低水平;③尿碘400 μg/g肌酐,水碘40 μg/l以上时,甲状腺肿 流行率又缓慢上升,所以水碘、尿碘含量和人群中甲状腺肿流行呈现底部较宽阔的“V”字形曲线的关系。本资料揭示尿碘400 μg/g肌酐,水碘40μg/l是人群中流行率最低水平的数值。当以甲状腺肿患病率3%做为判定地方性甲状腺肿的标准(1978年我国的地方性甲状腺肿防治工作标准)时,则尿碘的安全范围为50-1000 μg/g肌酐,水碘的安全范围为5-200 μg/l,低于或高于这个范围都可引起人群中甲状腺肿的流行。
Thyroid examination and urinary iodine and water iodine analysis of 40,000 people at several points in the mountains, mid-levels, plains and coasts revealed the iodine and iodine levels in areas ranging from “low iodine”, “medium iodine” to “high iodine” The prevalence of goitre in the population: ① urinary iodine at 50 μg / g creatinine, water iodine below 5 μg / l, the lower the iodine the higher the prevalence of goiter; ② urinary iodine from 50 μg / g creatinine, to 400 μg / g creatinine, water iodine from 5 μg / l to 40 μg / l, the lowest prevalence of goiter; ③ urine iodine 400 μg / g creatinine, water iodine 40 μg / l or more, the prevalence of goiter Slow rise, so the water iodine, urinary iodine content and population prevalence of goiter at the bottom of the broader “V” -shaped curve. This data discloses the urinary iodine 400 μg / g creatinine, water iodine 40 μg / l is the lowest prevalence in the population numerical. When the prevalence of goitre was 3% as the criterion for endemic goiter (the standard of endemic goiter prevention and control in our country in 1978), the safety range of urinary iodine was 50-1000 μg / g creatinine, water iodine The safe range of 5-200 μg / l, below or above this range can cause the crowd in the prevalence of goiter.