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目的探讨雪卡毒素中毒的原因、临床表现、治疗和预防。方法分析44例中毒病人的临床资料并结合文献资料。结果病人进食有毒海鱼肉、内脏或汤后经2~12h潜伏期,出现以急性胃肠炎为主的消化系统症状、以温度感觉倒错、运动乏力、唇舌及四肢麻痹、肌肉刺痛为主的神经系统症状、心率和血压变化的心血管系统症状。结论中毒后经2~12h潜伏期,出现消化、神经、心血管系统症状,以温度感觉倒错具有特征性,预后良好,病程2d至3周。为避免中毒,建议勿食用大型的深海鱼,特别是鱼头和内脏。
Objective To investigate the causes, clinical manifestation, treatment and prevention of ciguatoxin poisoning. Methods The clinical data of 44 cases of poisoning patients were analyzed and combined with the literatures. Results Patients fed with poisonous sea fish meat, viscera or soup after 2 ~ 12h incubation period, the main symptoms of acute gastroenteritis digestive system, temperature feeling inverted, fatigue, tongue and limb paralysis, muscle tingling mainly Neurological symptoms, heart rate and cardiovascular changes in blood pressure. Conclusion After 2 ~ 12h incubation period, the symptoms of digestive, neurological and cardiovascular diseases appear after incubation. The symptoms of temperature inversion are characteristic. The prognosis is good. The course of disease is from 2 days to 3 weeks. To avoid poisoning, it is recommended not to eat large deep-sea fish, especially the head and internal organs.