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短期给予气溶胶性重组人类脱氧核糖核酸酶于稳定期囊性纤维化成人的效果和安全性（ＲａｎａｓｉｎｈａＣ，ｅｔａｌ．Ｌａｎｃｅｔ，１９９３；３４２：１９９）慢性肺感染为囊性纤维化发病和死亡的主要原因。痰内高含量脱氧核糖核酸（ＤＮＡ）使得痰液粘稠并难于咳出。在...
Effects and safety of short-term administration of aerosol recombinant human deoxyribonuclease in stable stage cystic fibrosis in adults (Ranasinha C, et al. Lancet, 1993; 342: 199) Chronic pulmonary infection is the predominant cause of cystic fibrosis onset and death the reason. High levels of DNA in sputum make sputum thick and difficult to cough up. in...