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肺血管病变是先心病患儿的好发病变与主要死亡原因之一,影响生存的术后早期肺高压危象仍发生于某些先心病和可逆性肺血管病变患儿。而目前的常规血管扩张药物对肺血管床缺乏选择性,且应用中同时降低体循环压。吸入的一氧化氮(NO)经肺泡弥散
Pulmonary vascular disease is one of the major causes of morbidity and mortality in children with congenital heart disease. The risk of early postoperative pulmonary hypertension in children still occurs in some children with congenital heart disease and reversible pulmonary vascular disease. The current conventional vasodilator drugs on the lack of selectivity of the pulmonary vascular bed, and application while reducing systemic pressure. Inhaled nitric oxide (NO) is diffused through the alveoli