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本文研究了氟对大鼠自然杀伤（ＮＫ）细胞和白细胞介素－２（ＩＬ－２）的影响以及硼对氟的拮抗作用。大鼠饮用含氟水（１１０ｍｇ￣（Ｆ－）／Ｌ）和氟硼混合水（１１０ｍｇ￣（Ｆ－）＋４４ｍｇ￣（Ｂ３＋）／Ｌ）４个月，以饮用自来水为对照。研究结果表明氟可抑制大鼠脾脏ＮＫ细胞和ＩＬ－２的活性；硼在体外与氟混合后饮用，可拮抗氟引起的ＮＫ细胞和ＩＬ－２活性的降低，并使尿氟排出增加，骨氟含量下降，提示硼可拮抗氟的毒性。
This article studies the effects of fluoride on natural killer (NK) cells and interleukin-2 (IL-2) and the antagonistic effect of boron on fluoride in rats. Rats were drank with tap water for 4 months in drinking water containing fluoride (110 mg ~ (F -) / L) and boron fluoride mixed water (110 mg ~ (F ~) + 44 mg ~ (B3 +) / L) The results show that fluorine can inhibit the activity of NK cells and IL-2 in the spleen of rats. When boron is mixed with fluoride in vitro, boron can antagonize the decrease of fluoride-induced activity of NK cells and IL-2 and increase the excretion of urinary fluoride. Fluorine content decreased, suggesting boron can antagonize the toxicity of fluorine.