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目的比较前列腺癌与其他前列腺疾病之间鉴别诊断的3种指标的检测效能。方法从循证医学的角度,利用集成接收机运行曲线(SROC)法,对选入的19篇文献共计742名前列腺患者、1611名其他前列腺良性疾病患者进行研究。结果由SROC图可见,cPSA值的曲线下面积最大,C/T值次之,f/tPSA值再次。结论基于cPSA的血清学检测在中国人群前列腺癌的鉴别诊断中能发挥更加优异的作用;此外,f/tPSA值取0.10ng/ml时的检测效能要优于取0.15ng/ml时。
Objective To compare the detection efficacy of three indicators of differential diagnosis between prostate cancer and other prostate diseases. Methods From the perspective of evidence-based medicine, a total of 742 prostate patients and 1611 other patients with benign prostatic diseases were selected from the 19 selected articles by using integrated receiver operating curve (SROC). The results can be seen from the SROC map, cPSA value under the curve of the area under, C / T value, f / tPSA value again. Conclusions The serological test based on cPSA can play a more excellent role in the differential diagnosis of prostate cancer in Chinese population. In addition, the detection efficiency of f / tPSA at 0.10ng / ml is better than that of 0.15ng / ml.