论文部分内容阅读
目的观察美托洛尔治疗老年高血压伴2型糖尿病(dm)的疗效和不良反应。方法选择48例老年高血压伴DM患者,停服其他降压疗效不达标的降压药物,应用美托洛尔25～50mg,2次/d,口服,诊疗4周。治疗前、治疗结束后动态血压、心率监测1次,疗程中每周偶测血压、心律,并记录不良反应。结果治疗后无论偶测血压及动态血压,各指标较治疗前明显降低(P<0.01)。结论美托洛尔对老年人高血压伴DM降压效果较好,且无明显不良反应。
Objective To observe the efficacy and side effects of metoprolol in the treatment of type 2 diabetes mellitus (DM) in elderly patients with hypertension. Methods Forty-eight elderly hypertensive patients with DM were enrolled in this study. Other antihypertensive drugs with antihypertensive effect were discontinued. Metoprolol was administered 25 to 50 mg twice daily for 4 weeks. Before treatment, after treatment, ambulatory blood pressure and heart rate were monitored once a week. Even blood pressure and heart rate were recorded every week in the course of treatment. Adverse reactions were recorded. Results After treatment, regardless of the occasional blood pressure and ambulatory blood pressure, the indexes were significantly lower than those before treatment (P <0.01). Conclusion Metoprolol is effective in lowering blood pressure in elderly patients with DM and has no obvious adverse reactions.