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目的探讨固尔苏联合持续正压通气治疗新生儿呼吸窘迫综合征(neonatal respiratory distress syndrome,NRDS)的临床效果。方法选择2008年4月—2011年10月收治的NRDS患儿47例,其中选择2008年4月—2010年10月收治的22例为对照组,2010年11月—2011年10月收治的25例为治疗组。对照组给予常规治疗及持续正压通气治疗;治疗组在对照组治疗基础上加用固尔苏治疗,比较两组疗效。计数资料采用χ2检验,P<0.05为差异有统计学意义。结果对照组显效8例,占36.36%;好转6例,占27.27%;无效8例,占36.36%;总有效率63.64%。治疗组显效18例,占72.00%;好转4例,占16.00%;无效3例,占12.00%;总有效率88.00%。两组总有效率比较差异有统计学意义(χ2=3.875,P<0.05)。结论固尔苏联合持续正压通气治疗NRDS疗效优于单用持续正压通气,值得临床推广。
Objective To investigate the clinical efficacy of Gul-Su-Su combined with continuous positive pressure ventilation in the treatment of neonatal respiratory distress syndrome (NRDS). Methods Forty-seven children with NRDS who were admitted from April 2008 to October 2011 were selected. Among them, 22 cases were selected as control group from April 2008 to October 2010 and 25 cases were treated from November 2010 to October 2011 Example for the treatment group. The control group was given routine treatment and continuous positive pressure ventilation; the treatment group was treated with Guer Su on the basis of the control group, and the curative effect was compared between the two groups. Count data using χ2 test, P <0.05 for the difference was statistically significant. Results In the control group, 8 cases were markedly effective, accounting for 36.36%; 6 cases were improved, accounting for 27.27%; 8 cases were ineffective, accounting for 36.36%; and the total effective rate was 63.64%. The treatment group markedly effective in 18 cases, accounting for 72.00%; improved in 4 cases, accounting for 16.00%; invalid in 3 cases, accounting for 12.00%; total effective rate of 88.00%. The total effective rate between the two groups was statistically significant difference (χ2 = 3.875, P <0.05). Conclusion Gastrodia combined with continuous positive pressure ventilation is superior to continuous positive pressure ventilation in the treatment of NRDS, which is worthy of clinical promotion.