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目的探讨非酒精性脂肪性肝炎的临床特点及诊治方法。方法本文就146例非酒精性脂肪性肝炎的临床特点进行回顾性分析。结果NASH患者起病隐袭,多无症状或非特异性症状,且常与肥胖、高脂血症(尤其高三酰甘油)、2型糖尿病并存;肝功能ALT和GGT轻度升高;治疗上降脂、控制血糖与改善肝功相结合。结论NASH通过纠正危险因素,改善肝功能,增强肝抗氧化能力等治疗,肝功能可恢复正常,但随病程进展有部分演进为肝硬化。
Objective To investigate the clinical features and diagnosis and treatment of non-alcoholic steatohepatitis. Methods In this paper, 146 cases of non-alcoholic steatohepatitis clinical features were retrospectively analyzed. Results The onset of NASH patients was insidious, with many asymptomatic or nonspecific symptoms, and often coexisted with obesity, hyperlipidemia (especially hypertriglyceride) and type 2 diabetes mellitus. ALT and GGT of liver function were slightly elevated; Fat, blood sugar control and improve the combination of liver function. Conclusions NASH can regain normal liver function by correcting risk factors, improving liver function and enhancing liver antioxidant capacity. However, some progresses to cirrhosis with progression of disease.